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Depo-Testosterone

Depot-Testosterone (Testosterone Cypionate) Injection

What is Testosterone Cypionate?

Testosterone Cypionate is a long-acting injectable form of testosterone, used to treat men with low or no testosterone (hypogonadism). It helps restore natural hormone levels to improve energy, strength, mood, and sexual function.

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  • Route: Intramuscular (IM) or Subcutaneous (SC) injection
  • Typical Frequency: Every 7–10 days for IM use
  • Supplied As: 100 or 200 mg/mL in a sterile oil base
  • We provide clear guidance on injection technique and rotating sites.

With regular dosing and follow-up, you may notice:

  • Increased energy and focus
  • Improved muscle mass and fat distribution
  • Better mood and motivation
  • Enhanced libido and erectile function
  • Deeper sleep
  • Side effects can include acne, increased red blood cell count, or mood changes.
  • Testosterone can convert to DHT (may affect hair, skin) and estradiol (can impact mood, fluid retention).
  • May affect fertility—speak to your provider if you plan to have children.
  • Common labs: Total & Free Testosterone, Estradiol, PSA, SHBG, Hematocrit, DHT, FSH/LH
  • Avoid ejaculation for 48 hours before a PSA test

⚠️ Testosterone Black Box Warning

1. Secondary Exposure Risk (Topical Products)

  • Children and women can be harmed if they come into contact with skin where testosterone gel or cream has been applied.
  • Can cause early puberty in children and signs of virilization (e.g., hair growth, acne) in women.
  • Users must wash hands after application and cover the application site.

2. Blood Pressure Increase (Injectable Forms)

  • Certain testosterone products (e.g., testosterone undecanoate like Aveed) carry a risk of serious blood pressure increases, which may raise the risk of heart attack, stroke, or death.
  • Monitor blood pressure regularly during treatment.
  • If you have sleep apnea, talk with your doctor. Sometimes, sleep apnea has gotten worse in people using testosterone.
  • If you’re trying to have children, talk to your doctor—testosterone lowers sperm count

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The information and videos found here are for educational purposes only and do not replace a consultation with a pharmacist. For personalized guidance, please contact us to speak directly with a pharmacist about your medication.

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Disclaimer:
The drug information provided is for informational and educational purposes only. The products or formulations discussed may not be approved by the U.S. Food and Drug Administration (FDA). This information is not intended to diagnose, treat, cure, or prevent any disease, nor does it replace a consultation with a qualified pharmacist or healthcare provider. Always seek the advice of your healthcare professional regarding any questions you may have about a medication or treatment.

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