Fight PCOS, Diabetes, and Infertility with Myoinositol
Do you have polycystic ovarian syndrome (PCOS)? Are you confused about how it affects your overall health? Do you know what to expect when coping with PCOS?
PCOS (Polycystic Ovary Syndrome) is a syndrome of hormonal imbalance that causes your ovaries to release eggs irregularly. Sometimes, this imbalance causes them to stop being released at all.
The hormonal imbalances that cause and maintain PCOS are complex and intertwined. The most common causes include the overproduction of insulin and androgens (testosterone and DHEA). The overproduction of these hormones is linked to other diseases and disorders such as weight gain, diabetes, excess facial hair, acne, and infertility.
This article will review some of the most frequent questions related to PCOS like:
- Can you cure PCOS?
- Why does PCOS cause so many other diseases?
- Why are you gaining weight with PCOS, and how to lose this excess weight?
- Why does PCOS affect fertility?
- How can the latest myoinositol (MI) treatments help you get pregnant?
And many more. So, keep reading!
Women who suffer from PCOS struggle with 3 main issues:
- Insulin resistance. Women with PCOS have a 40% higher risk of developing diabetes as a result of insulin resistance.
- Problems with conceiving. Up to 95% of women who have lost the ability to ovulate, and who are making appointments with fertility specialists have PCOS.
- Acne & Excess Hair. PCOS symptoms often include excesses in androgens which cause acne and excess facial hair. In fact, 40% of women with acne are diagnosed with PCOS, while 70% of women with PCOS will complain of excess hair growth.
A well-balanced lifestyle and taking prescribed treatment can improve PCOS symptoms and increase your chances of getting pregnant. However, there’s no proven way for a woman to completely eliminate PCOS. Current treatment models for PCOS revolve around the following:
- Making lifestyle changes. Doing regular cardio exercises and going on a low carb/sugar diet will help with insulin resistance and weight regulation.
- Taking prescribed medications like metformin and clomiphene. Metformin is a medication used to treat diabetes that helps to sensitizes your cells to better balance your blood sugar levels. Clomiphene is a medication that can help increase your chances of getting pregnant by helping your body to stimulate ovulation.
Besides metformin and clomiphene, taking inositol can be extremely helpful. Inositol is a compound found in nuts, grains, fruits, and beans. It has been shown to treat the root cause of PCOS and has been shown to produce numerous other health improvements.
The latest research indicates that inositol helps women with PCOS by treating acne, excess hair growth, weight gain and infertility caused by increased androgens and insulin resistance.
Inositol, also known as Vitamin B8, has several important functions.
- It’s a component of the cell’s membranes providing a structural role.
- It modulates the actions of insulin, helping to transport sugar into cells.
- It may help balance the neurotransmitters in your brain (serotonin and dopamine)
Inositol, which includes myo-inositol (MI) and D-chiro-inositol (DCI), act as messengers in the body’s cells. They help to regulate other hormones such as:
- Thyroid Stimulating Hormone (TSH) – Stimulates the production of thyroid hormones
- Insulin – Manages your blood sugar
- Follicle Simulating Hormone (FSH) – Responsible for selecting a dominant follicle for ovulation and stimulating estrogen production
Let’s begin with inositol. The ratio of inositol (MI and DCI) in your body can affect how well your tissues and organs function. For example, a MI:DCI ratio of 40:1 is considered to be healthy. This ratio correlates to proper ovarian function, ovulation, and fertility. Women with PCOS, on the other hand, have an average MI:DCI ratio of 0.2:1.
Epimerase is an enzyme that transforms MI to DCI. Insulin resistance affects epimerase function and the balance of this ratio. This can lead to increased insulin levels, diabetes, and infertility.
Higher than normal levels of insulin in the body is destructive to the body’s normal signalling. High insulin levels signal the body’s ovaries to produce high amounts of androgens (like testosterone). This causes the body to store fat and cause symptoms such as acne and excess hair growth.
PCOS creates a vicious cycle of weight gain and hormonal imbalances. Here is what this vicious cycle looks like:
- Hyperandrogenemia (Too much testosterone and DHEA) worsens insulin resistance.
- Increases in androgens signal fatty acids storge in the body. This also worsens insulin resistance.
- Insulin resistance and high insulin levels contributes to obesity. This leads to increased androgen production in the ovaries and adrenals.
- Obesity also links with leptin resistance. Leptin is a hormone that controls appetite. When leptin is elevated, it increases the risks from obesity-related diseases (type 2 diabetes, autoimmune disease, cardiovascular disease, etc.)
- With elevated leptin, you become more hungry, which further increases insulin levels, and the cycle continues.
When the optimal ratio of DCI and MI is out of balance, the hormone, FSH, can’t work correctly. FSH is needed to help the ovary select a dominant follicle every month which will eventually release an egg to be potentially fertilized. Normally, a dominant follicle would produce a lot of estrogen, preparing the uterus for implantation. It would do so until estrogen hits a critical level, which helps to trigger ovulation. If FSH and estrogen aren’t right, then fertility goes out the window.
But, PCOS doesn’t only cause problems with fertility. It can also cause problems during pregnancy as well. Lower production of DCI in fat tissues, liver, and skeletal muscles, is associated with pre-eclampsia. Pre-eclampsia is a term used for high blood pressure in pregnant women. Pre-eclampsia can lead to kidney and liver damage.
There are a several research findings that reveal evidence in support of the use of myoinositol in patients suffering from PCOS. These are highlighted here:
In one study, 25 women with PCOS took 2 g of myo-inositol twice a day for six months. An astounding 22 women regained their cycles. A total of 18 women proceeded to have regular periods.
This study resulted in 10 women becoming pregnant during the six-month period.
Another study used a similar treatment and recorded pregnancies in 15 out of 50 women who participated in the study. Ten women had clinical pregnancies, and eight women gave birth. Numerous other improvements were recorded in this study as well.
A 2009 study tested the effectiveness of MI over metformin in women with PCOS. In this study, 2 groups of 60 women were given different medications, and their conditions were tracked and measured. The first group took 1,500 mg of metformin daily, while the second group took 4 g of MI per day.
Over a half (65%) of the women taking MI restored their ovulation compared to 50% of those who took metformin. In addition, 18% of women on MI were able to get pregnant compared to 11% of those who took metformin.
A study done in Iraq recorded a notable decrease in the body mass index (weight loss) in women who took 500 mg of inositol, 850mg of metformin, and 500 mg of choline.
The largest study we could find included 180 women with PCOS who were divided up according to their clinical features and treated for 6 months.
All of these studies support the use of MI in breaking the cycle of insulin resistance, androgen excess, weight gain, and infertility
Untreated PCOS can significantly increase the risk of cardiovascular disease, high blood pressure, insulin resistance, and obesity. The latter two contribute greatly to issues with fertility and pre-eclampsia during pregnancy. Fortunately, studies report that PCOS can be successfully controlled with the use of myo-inositol to help reduce insulin resistance, improve ovarian function, and reduce androgen levels. Because of these benefits, myoinositol has been reported to improve fertility.
Start your healing process today!
The staff at Harbor Compounding Pharmacy are not just pharmacists. They are also scientists. They scour medical research. They look at the latest research in the causes of disease. They find solutions that can potentially treat these causes. And because they are also drug formulation experts, they bring these solutions to life, helping those that want and need affordable, research based, and safe therapeutic options.
PCOS Suppress is a pharmacist formulated supplement featuring myoinositol. It also contains tyrosine, folic acid, selenium and chromium which can support healthy thyroid function.
Don’t wait any longer to get help for your PCOS. Call one of our expert pharmacists to Place your order today!
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